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Publications

In Vivo Polymer Mechanochemistry with Polynucleotides - PubMed (nih.gov)

Ishaqat A, Hahmann J, Lin C, Zhang X, He C, Rath WH, Habib P, Sahnoun SEM, Rahimi K, Vinokur R,

Mottaghy FM, Göstl R, Bartneck M, Herrmann A.

Adv Mater. 2024, e2403752. doi: 10.1002/adma.202403752. Epub ahead of print. PMID: 38804595.

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mRNA Sonotransfection of Tumors with Polymeric Microbubbles: Co-Formulation versus Co-Administration - PubMed (nih.gov)

J. Chen, B. Wang, Y. Wang, H. Radermacher, J. Qi, J. Momoh, T. Lammers, Y. Shi, A. Rix, F. Kiessling.

Adv. Sci. 2024, 11, 2306139. https://doi.org/10.1002/advs.202306139

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Identifying individuals at risk of needing CKD associated medications in a European kidney disease cohort - PubMed (nih.gov)

Eleni Stamellou, Turgay Saritas, Marc Froissart, Florian Kronenberg, Peter Sternvinkel, David C. Wheeler, Kai-Uwe Eckardt,

Jürgen Floege, James Fotheringham.

BMC Nephrol. 2024, 25(1):60.

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Long-term outcomes of adults with FSGS in the German Chronic Kidney Disease cohort - PubMed (nih.gov)

Eleni Stamellou*, Jennifer Nadal,  Bruce Hendry,  Alex Mercer, Wibke Bechtel-Walz,  Mario Schiffer,  Kai-Uwe Eckardt,  Rafael Kramann, Marcus J Moeller,  Jürgen Floege on behalf of the GCKD study investigators.

Clinical Kidney Journal 2024, sfae131, https://doi.org/10.1093/ckj/sfae131.

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Altered biodistribution of [68Ga]Ga-DOTA-TOC during somatostatin analogue treatment - PubMed (nih.gov)

van de Weijer T, Bemer F, de Vos-Geelen J, Hermans B, Mitea C, van der Pol JAJ, Lodewick T, Wildberger JE, Mottaghy FM

Eur J Nucl Med Mol Imaging. 2024, doi: 10.1007/s00259-024-06659-0. Epub ahead of print. PMID: 38403723.

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Pathophysiologic Mapping of Chronic Liver Diseases With Longitudinal Multiparametric MRI in Animal Models - PubMed (nih.gov)

Baskaya F, Lemainque T, Klinkhammer B, Koletnik S, von Stillfried S, Talbot SR, Boor P, Schulz V, Lederle W, Kiessling F. 

Invest Radiol. 2024, doi: 10.1097/RLI.0000000000001075. 

 

Lineage tracing reveals transient phenotypic adaptation of tubular cells during acute kidney injury - PubMed (nih.gov)

Buse M, Cheng M, Jankowski V, Lellig M, Sterzer V, Strieder T, Leuchtle K, Martin IV, Seikrit C, Brinkkoettter P, Crispatzu G, Floege J, Boor P, Speer T, Kramann R, Ostendorf T, Moeller MJ, Costa IG, Stamellou E:

iScience  2024, 27(3):109255 doi: 10.1016/j.isci.2024.109255

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Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis -

PubMed (nih.gov)

Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek AL, Abbas T, Abdelmageed N, Morad SAF, Morad W, Hamdy A, Albrecht W, Kittana N, Assali M, Vartak N, van Thriel C, Sous A, Nell P, Villar-Fernandez M, Cadenas C, Genc E, Marchan R, Luedde T, Åkerblad P, Mattsson J, Marschall HU, Hoehme S, Stirnimann G, Schwab M, Boor P, Amann K, Schmitz J, Bräsen JH, Rahnenführer J, Edlund K, Karpen SJ, Simbrunner B, Reiberger T, Mandorfer M, Trauner M, Dawson PA, Lindström E, Hengstler JG:

J Hepatol. 2024, 6:S0168-8278(23)05235-2. doi: 10.1016/j.jhep.2023.10.035. Online ahead of print.

 

Semiautomated pipeline for quantitative analysis of heart histopathology - PubMed (nih.gov)

Droste P, Wong DWL, Hohl M, von Stillfried S, Klinkhammer BM, Boor P:

J Transl Med. 2024, 21:666

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The role of desmoglein-2 in kidney disease - PubMed (nih.gov)

Tong Xu, Lea Herkens, Ting Jia, Barbara M. Klinkhammer, Sebastian Kant, Claudia A. Krusche, Eva M. Buhl, Sikander Hayat, Jürgen Floege, Pavel Strnad, Rafael Kramann, Sonja Djudjaj*, Peter Boor*:

Kidney Int. 2024, 105(5):1035-1048. doi: 10.1016/j.kint.2024.01.037. Epub 2024 Feb 21.

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Histopathological biomarkers for predicting the tumour accumulation of nanomedicines - PubMed (nih.gov)

May JN, Moss JI, Mueller F, Golombek SK, Biancacci I, Rizzo L, Elshafei AS, Gremse F, Pola R, Pechar M, Etrych T, Becker S, Trautwein C, Bülow RD, Boor P, Knuechel R, von Stillfried S, Storm G, Puri S, Barry ST, Schulz V, Kiessling F, Ashford MB, Lammers T:

Nat Biomed Eng. 2024, doi: 10.1038/s41551-024-01197-4.

 

A Machine Learning-Driven Virtual Biopsy System For Kidney Transplant Patients - PubMed (nih.gov)

Yoo D, Divard G, Raynaud M, Cohen A, Mone TD, Rosenthal JT, Bentall AJ, Stegall MD, Naesens M, Zhang H, Wang C, Gueguen J, Kamar N, Bouquegneau A, Batal I, Coley SM, Gill JS, Oppenheimer F, De Sousa-Amorim E, Kuypers DRJ, Durrbach A, Seron D, Rabant M, Van Huyen JD, Campbell P, Shojai S, Mengel M, Bestard O, Basic-Jukic N, Jurić I, Boor P, Cornell LD, Alexander MP, Toby Coates P, Legendre C, Reese PP, Lefaucheur C, Aubert O, Loupy A:

Nat Commun. 2024, 5(1):554. doi: 10.1038/s41467-023-44595-z.

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[Advances in computational quantitative nephropathology] - PubMed (nih.gov)

Bülow RD, Droste P, Boor P:

Pathologie (Heidelb). 2024, doi: 10.1007/s00292-024-01300-1. Online ahead of print.

 

[Artificial intelligence in kidney transplant pathology] - PubMed (nih.gov)

Bülow RD, Lan YC, Amann K, Boor P:

Pathologie (Heidelb). 2024, doi: 10.1007/s00292-024-01324-7.

 

Spatial multi-omics: novel tools to study the complexity of cardiovascular diseases - PubMed (nih.gov)

Kiessling P, Kuppe C.

Genome Med. 2024, 16(1):14. doi: 10.1186/s13073-024-01282-y. PMID: 38238823; PMCID: PMC10795303

 

New tools to study renal fibrogenesis - PubMed (nih.gov)

Liao X, Scheidereit E, Kuppe C

Curr Opin Nephrol Hypertens. 2024, 33(4):420-426. doi: 10.1097/MNH.0000000000000988. Epub 2024 Apr 8. PMID: 38587103; PMCID: PMC11139246

 

Post-translational modifications in kidney diseases and associated cardiovascular risk - PubMed (nih.gov)

Noels H, Jankowski V, Schunk SJ, Vanholder R, Kalim S, Jankowski J:

Nat Rev Nephrol. 2024, oi: 10.1038/s41581-024-00837-x. Online ahead of print.

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Mechanisms of kidney fibrosis and routes towards therapy - PubMed (nih.gov)

Yamashita N, Kramann R:

Trends Endocrinol Metab 2024, 35(1):31-48.

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Cardiovascular Consequences of Uremic Metabolites: an Overview of the Involved Signaling Pathways - PubMed (nih.gov)

Curaj A, Vanholder R, Loscalzo J, Quach K, Wu Z, Jankowski V, Jankowski J.

Circ Res. 2024, 134(5):592-613 PMID: 38422175.

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Perihilar FSGS lesions originate from flat parietal epithelial cells.

Arnaldo Chia-Gil, Jürgen Floege, Eleni Stamellou*,#, and Marcus J. Moeller

J Nephrol. 2024 Feb 1.; doi: 10.1007/s40620-024-01886-y. Online ahead of print.

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A new alternative: inhibiting complement activation in patients with IgA nephropathy - PubMed (nih.gov)

Floege J.  Kidney Int. 2024.

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Detection of PatIent-Level distances from single cell genomics and pathomics data with

Optimal Transport (PILOT) - PubMed (nih.gov)

Joodaki, M., Shaigan, M., Parra, V., Roman, D.B., Nagai. J, Mingbo, C., Barratt, J., Roberts, I.S.D., Coppo, R.,

Kramann, R., Boor, P., Costa, I.G. bioRxiv [paper | software]., 2022.

Mol Syst Biol., 2024 Feb;20(2):57-74.; doi: 10.1038/s44320-023-00003-8. Epub 2023 Dec 19.

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PDGF-D is dispensable for the development and progression of murine Alport syndrome - PubMed (nih.gov)

Firat EAM, Buhl EM, Bouteldja N, Smeets B, Eriksson U, Boor P, Klinkhammer BM.

Am J Pathol. 2024 Feb 1:S0002-9440(24)00036-1.;  doi: 10.1016/j.ajpath.2023.12.009. Online ahead of print.

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Sodium-glucose cotransporter 2 inhibition in primary and secondary glomerulonephritis.

Caravaca-Fontán F, Stevens K, Padrón M, Huerta A, Montomoli M, Villa J, González F, Vega C, López Mendoza M, Fernández L, Shabaka A, Rodríguez-Moreno A, Martín-Gómez A, Labrador PJ, Molina Andújar A, Soler MCP, Martín-Penagos L, Yerovi E, Medina Zahonero L, De La Flor JC, Mon C, Ibernon M, Gómez AR, Miquel R, Sierra M, Mascarós V, Luzardo L, Papasotiriou M, Arroyo D, Verdalles Ú, Martínez-Miguel P, Ramírez-Guerrero G, Pampa-Saico S, Moral Berrio E, Canga JLP, Tarragón B, Gómez PF, Regidor D, Relea J, Xipell M, Gómez CA, Navarro M, Álvarez Á, Rivas B, Quintana LF, Gutiérrez E, Pérez-Valdivia MÁ, Odler B, Kronbichler A, Geddes C, Anders HJ, Floege J, Fernández-Juárez G, Praga M; Spanish Group for the Study of Glomerular Diseases (GLOSEN)

and the Immunonephrology Working Group of the European Renal Association (ERA)..

Nephrol Dial Transplant. 2023 Aug 7:gfad175. doi: 10.1093/ndt/gfad175. Online ahead of print.

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Validation of Dual-Action Chemo-Radio-Labeled Nanocarriers with High Efficacy against Triple-Negative Breast Cancer - PubMed (nih.gov)

Ilyas S, Sahnoun SEM, Szymura A, Pes J, Habib S, Florea A, Schäfer L, Buhl EM, Morgenroth A, Habib P, Mottaghy FM*, Mathur S*.

ACS Appl Mater Interfaces. 2023 25;15(42):48963-48977. doi: 10.1021/acsami.3c10579. Epub 2023 Oct 13. PMID: 37831583.

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Glycosylation Analysis of Urinary Peptidome Highlights IGF2 Glycopeptides in Association with CKD - PubMed (nih.gov)

Lohia S, Latosinska A, Zoidakis J, Makridakis M, Mischak H, Glorieux G, Vlahou A, Jankowski V.

Int J Mol Sci. 2023, 24(6):5402.doi:10.3390/ijms24065402.

 

Intermediate filament network perturbation in the C. elegans intestine causes systemic dysfunctions - PubMed (nih.gov)

Geisler F ,  Remmelzwaal S, Jankowski V, Schmidt R, Boxem M , Leube RE

Elife 2023, 7:12e82333.doi:10.7554/eLife.82333.

 

A Spp1-macrophage-platelet-axis orchestrates myofibroblast activation in fibrosis.

Hoeft K, Schaefer GJL, Kim H, Schumacher D, Long Q, Klinkhammer BM, Peisker F, Koch L, Wahida A Halder M, Ziegler S, Liehn E, Kuppe C, Kranz J, Menzel S, Boor P, Schneider RK, Hayat S, Kramann R:

Cell Reports 2023, 42(2)112131

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99mTc‑labeled single-domain antibody for SPECT/CT assessment of HER2 expression in diverse cancer types - PubMed (nih.gov)

Altunay B, Goedicke A, Winz OH, Hertel F, von Mallek D, Meszaros LK, Chand G, Biersack HJ, Stickeler E, Krauss K, Mottaghy FM.

Eur J Nucl Med Mol Imaging. 2023, 50(4):1005-1013. doi: 10.1007/s00259-022-06066-3. Epub 2022 Dec 9. PMID: 36482076

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ULTRA-SR Challenge: Assessment of Ultrasound Localization and TRacking Algorithms for Super-Resolution Imaging - PubMed (nih.gov)

Lerendegui M, Riemer K, Papageorgiou G, Wang B, Arthur L, Chavignon A, Zhang T, Couture O, Huang P, Ashikuzzaman M, Dencks S, Dunsby C, Helfield B, Jensen JA, Lisson T, Lowerison MR, Rivaz H, Samir AE, Schmitz G, Schoen S, Sloun RV, Song P, Stevens T, Yan J, Sboros V, Tang MX

IEEE Trans Med Imaging. 2023, PP. doi: 10.1109/TMI.2024.3388048. Epub ahead of print. PMID: 38607705.

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Molecular Ultrasound Imaging Depicts the Modulation of Tumor Angiogenesis by Acetylsalicylic Acid - PubMed (nih.gov)

Mueller-Diesing F, Lederle W, Rix A, Koletnik S, Doleschel D, Snelting M, Gremse F, Kiessling F.

Int J Mol Sci. 2023, 24(8):7060. doi: 10.3390/ijms24087060. PMID: 37108226; PMCID: PMC10139153.

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Finerenone Added to RAS/SGLT2 Blockade for CKD in Alport Syndrome. Results of a Randomized Controlled Trial

with Col4a3-/- Mice - PubMed (nih.gov)

Zhu Z, Rosenkranz KA, Kusunoki Y, Li C, Klaus M, Gross O, Angelotti ML, Antonelli G, Cirillo L, Romagnani P,

Bouteldja N, Sadr AV, Bülow RD, Boor P, Anders HJ:

J Am Soc Nephrol. 2023, 34:1513-1520

 

Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice

with obstructive cholestasis - PubMed (nih.gov)

Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek AL, Abbas T, Abdelmageed N, Morad SAF, Morad W, Hamdy A, Albrecht W, Kittana N, Assali M, Vartak N, van Thriel C, Sous A, Nell P, Villar-Fernandez M, Cadenas C, Genc E, Marchan R, Luedde T, Åkerblad P, Mattsson J, Marschall HU, Hoehme S, Stirnimann G, Schwab M, Boor P, Amann K, Schmitz J, Bräsen JH, Rahnenführer J, Edlund K, Karpen SJ, Simbrunner B, Reiberger T, Mandorfer M, Trauner M, Dawson PA, Lindström E, Hengstler JG:

J Hepatol. 2024, 6:S0168-8278(23)05235-2. doi: 10.1016/j.jhep.2023.10.035. Online ahead of print.

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Multiple urinary peptides display distinct sex-specific distribution - PubMed (nih.gov)

Mina I, Mavrogeogis E, Siwy J, Stojanov R, Mischak H, Latosinska A, Jankowski V:

Proteomics 2023, 2300227. Doi.org/10.102/pmic20230027

 

Mapping cardiac remodeling in chronic kidney disease - PubMed (nih.gov)

Kaesler N, Cheng M, Nagai J, O'Sullivan J, Peisker F, Bindels EMJ, Babler A, Moellmann J, Droste P, Franciosa G, Dugourd A, Saez-Rodriguez J, Neuss S, Lehrke M, Boor P, Goettsch C, Olsen JV, Speer T, Lu TS, Lim K, Floege J, Denby L, Costa I, Kramann R:

Sci Adv. 2023, 9:eadj4846

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Ultrasound localization microscopy - PubMed (nih.gov)

Dencks S, Schmitz G.

Z Med Phys. 2023, 33(3):292-308. doi: 10.1016/j.zemedi.2023.02.004. Epub 2023 Jun 15. PMID: 37328329; PMCID: PMC10517400.

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Banff Digital Pathology Working Group: Image Bank, Artificial Intelligence Algorithm, and Challenge Trial Developments - PubMed (nih.gov)

Farris AB, Alexander MP, Balis UGJ, Barisoni L, Boor P, Bülow RD, Cornell LD, Demetris AJ, Farkash E, Hermsen M, Hogan J, Kain R, Kers J, Kong J, Levenson RM, Loupy A, Naesens M, Sarder P, Tomaszewski JE, van der Laak J, van Midden D, Yagi Y, Solez K:

Transpl Int. 2023, 36:11783

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Kidney fibrosis: Emerging diagnostic and therapeutic strategies - PubMed (nih.gov)

Klinkhammer BM, Boor P:

Mol Aspects Med. 2023, 10.1016/j.mam.2023.101206. Epub 2023 Aug 3.

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Fibrosis in Pathology of Heart and Kidney: From Deep RNA-Sequencing to Novel Molecular Targets - PubMed (nih.gov)

Schreibing F, Anslinger M, Kramann R:

Circulation Research 2023, 132(8):1013-1033. doi: 10.1161/CIRCRESAHA.122.321761.

 

Metabolic reprogramming heterogeneity in chronic kidney disease - PubMed (nih.gov)

Miguel V, Kramann R:

FEBS Open Bio 2023, 13(7):1154-1163. doi: 10.1002/2211-5463.13568. Online ahead of print.

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Inhibition of the glucocorticoid receptor attenuates proteinuric kidney diseases in multiple species - PubMed (nih.gov)

Eleni Stamellou, Shipra Agrawal, Florian Siegerist,  Christoph Kuppe, Tammo Ostendorf, Tim Lange, Eva Miriam Buhl, Jessica Alam, Thiago Strieder, Peter Boor, Hermann-Josef Gröne, Jürgen Floege, William E. Smoyer, Nicole Endlich and Marcus J. Moeller

Nephrol Dial Transplant., 2023 Nov 30:gfad254.  doi: 10.1093/ndt/gfad254. Online ahead of print.

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IgA nephropathy

Stamellou, E., Seikrit, C., Tang, S.C.W. et al. IgA nephropathy.

Nat Rev Dis Primers 9, 67 (2023). https://doi.org/10.1038/s41572-023-00476-9

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Targeted-release budesonide modifies key pathogenic biomarkers in immunoglobulin A nephropathy:

insights from the NEFIGAN trial - PubMed (nih.gov)

Wimbury D, Muto M, Bhachu JS, Scionti K, Brown J, Molyneux K, Seikrit C, Maixnerová D, Pérez-Alós L, Garred P, Floege J, TesaÅ™ V, Fellstrom B, Coppo R, Barratt J. 

Kidney Int. 2024 Feb;105(2):381-388.;  doi: 10.1016/j.kint.2023.11.003. Epub 2023 Nov 25.

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3D Printed Tubulointerstitium Chip as an In Vitro Testing Platform - PubMed (nih.gov)

Addario G, Eussen D, Djudjaj S, Boor P, Moroni L, Mota C.

Macromol Biosci. 2023 Nov 23:e2300440.;  doi: 10.1002/mabi.202300440. Online ahead of print.

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Operational greenhouse-gas emissions of deep learning in digital pathology: a modelling study - PubMed (nih.gov)

Vafaei Sadr A, Bülow R, von Stillfried S, Schmitz NEJ, Pilva P, Hölscher DL, Ha PP, Schweiker M, Boor P.

Lancet Digit Health. 2024 Jan;6(1):e58-e69.;  doi: 10.1016/S2589-7500(23)00219-4. Epub 2023 Nov 22.

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Inflammation and vascular remodeling in COVID-19 hearts - PubMed (nih.gov)

Werlein C, Ackermann M, Stark H, Shah HR, Tzankov A, Haslbauer JD, von Stillfried S, Bülow RD, El-Armouche A, Kuenzel S, Robertus JL, Reichardt M, Haverich A, Höfer A, Neubert L, Plucinski E, Braubach P, Verleden S, Salditt T, Marx N, Welte T, Bauersachs J, Kreipe HH, Mentzer SJ, Boor P, Black SM, Länger F, Kuehnel M, Jonigk D.

Angiogenesis. 2023 May;26(2):233-248. doi: 10.1007/s10456-022-09860-7. Epub 2022 Nov 12.

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CKD therapy to improve outcomes of immune-mediated glomerular diseases.

Anders HJ, Fernandez-Juarez GM, Vaglio A, Romagnani P, Floege J.

Nephrol Dial Transplant. 2023 May 22:gfad069. doi: 10.1093/ndt/gfad069. Online ahead of print.

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Ultrasound Localization Microscopy for Breast Cancer Imaging in Patients: Protocol Optimization and Comparison with Shear Wave Elastography - PubMed (nih.gov)

Porte C, Lisson T, Kohlen M, von Maltzahn F, Dencks S, von Stillfried S, Piepenbrock M, Rix A, Dasgupta A, Koczera P, Boor P, Stickeler E, Schmitz G, Kiessling F.

Ultrasound Med Biol. 2024 Jan;50(1):57-66. doi: 10.1016/j.ultrasmedbio.2023.09.001. Epub 2023 Oct 6.

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Semiautomated pipeline for quantitative analysis of heart histopathology - PubMed (nih.gov)

Droste P, Wong DWL, Hohl M, von Stillfried S, Klinkhammer BM, Boor P.

J Transl Med. 2023 Sep 26;21(1):666.;  doi: 10.1186/s12967-023-04544-2.

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Dissecting gene regulation with multimodal sequencing - PubMed (nih.gov)

Costa, I.G.

Nat Methods, 2023 Sep;20(9):1282-1284. doi: 10.1038/s41592-023-01957-1.

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A spatially resolved atlas of healthy and injured kidney cell states. 

Kuppe C, Kramann R.

Nephrol Dial Transplant. 2023 Sep 14:gfad203. doi: 10.1093/ndt/gfad203. Online ahead of print.

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Efficacy and safety of a targeted-release formulation of budesonide in patients with primary IgA nephropathy (NefIgArd): 2-year results from a randomised phase 3 trial.

Lafayette R, Kristensen J, Stone A, Floege J, TesaÅ™ V, Trimarchi H, Zhang H, Eren N, Paliege A, Reich HN, Rovin BH, Barratt J

NefIgArd trial investigators. Lancet. 2023 Sep 9;402(10405):859-870.

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Novel agents for treating IgA nephropathy.

Kunter U, Seikrit C, Floege J.

Curr Opin Nephrol Hypertens. 2023 Sep 1;32(5):418-426. doi: 10.1097/MNH.0000000000000902. Epub 2023 May 26.

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Extending the landscape of omics technologies by pathomics - PubMed (nih.gov)

Bülow, R.D., Hölscher, D.L., Costa, I.G., Boor, P.,

npj Syst Biol Appl. 2023 Aug 7;9(1):38.;  doi: 10.1038/s41540-023-00301-9.

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2,8-Dihydroxyadenine-induced nephropathy causes hexosylceramide accumulation with increased mTOR signaling, reduced levels of protective SirT3 expression and impaired renal mitochondrial function - PubMed (nih.gov)

Moellmann J, Krueger K, Wong DWL, Klinkhammer BM, Buhl EM, Dehairs J, Swinnen JV, Noels H, Jankowski J, Lebherz C, Boor P, Marx N, Lehrke M.

Biochim Biophys Acta Mol Basis Dis. 2024 Jan;1870(1):166825. doi: 10.1016/j.bbadis.2023.166825. Epub 2023 Aug 1.

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Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer - PubMed (nih.gov)

Huth S, Huth L, Heise R, Marquardt Y, Lopopolo L, Piecychna M, Boor P, Fingerle-Rowson G, Kapurniotu A, Yazdi AS, Bucala R, Bernhagen J, Baron JM.

Sci Rep. 2023 Jul 18;13(1):11611. doi: 10.1038/s41598-023-38748-9.

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Multi-institutional PET/CT image segmentation using federated deep transformer learning - PubMed (nih.gov)

Shiri I, Razeghi B, Vafaei Sadr A, Amini M, Salimi Y, Ferdowsi S, Boor P, Gündüz D, Voloshynovskiy S, Zaidi H.

Comput Methods Programs Biomed. 2023 Oct;240:107706. doi: 10.1016/j.cmpb.2023.107706. Epub 2023 Jul 12.

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Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy - PubMed (nih.gov)

Kiryluk K, Sanchez-Rodriguez E, Zhou XJ, Zanoni F, Liu L, Mladkova N, Khan A, Marasa M, Zhang JY, Balderes O, Sanna-Cherchi S, Bomback AS, Canetta PA, Appel GB, Radhakrishnan J, Trimarchi H, Sprangers B, Cattran DC, Reich H, Pei Y, Ravani P, Galesic K, Maixnerova D, Tesar V, Stengel B, Metzger M, Canaud G, Maillard N, Berthoux F, Berthelot L, Pillebout E, Monteiro R, Nelson R, Wyatt RJ, Smoyer W, Mahan J, Samhar AA, Hidalgo G, Quiroga A, Weng P, Sreedharan R, Selewski D, Davis K, Kallash M, Vasylyeva TL, Rheault M, Chishti A, Ranch D, Wenderfer SE, Samsonov D, Claes DJ, Akchurin O, Goumenos D, Stangou M, Nagy J, Kovacs T, Fiaccadori E, Amoroso A, Barlassina C, Cusi D, Del Vecchio L, Battaglia GG, Bodria M, Boer E, Bono L, Boscutti G, Caridi G, Lugani F, Ghiggeri G, Coppo R, Peruzzi L, Esposito V, Esposito C, Feriozzi S, Polci R, Frasca G, Galliani M, Garozzo M, Mitrotti A, Gesualdo L, Granata S, Zaza G, Londrino F, Magistroni R, Pisani I, Magnano A, Marcantoni C, Messa P, Mignani R, Pani A, Ponticelli C, Roccatello D, Salvadori M, Salvi E, Santoro D, Gembillo G, Savoldi S, Spotti D, Zamboli P, Izzi C, Alberici F, Delbarba E, Florczak M, Krata N, Mucha K, PÄ…czek L, Niemczyk S, Mosz…

Nat Genet. 2023 Jul;55(7):1091-1105. doi: 10.1038/s41588-023-01422-x. Epub 2023 Jun 19.

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A meta-analysis of GFR slope as a surrogate endpoint for kidney failure.

Inker LA, Collier W, Greene T, Miao S, Chaudhari J, Appel GB, Badve SV, Caravaca-Fontán F, Del Vecchio L, Floege J, Goicoechea M, Haaland B, Herrington WG, Imai E, Jafar TH, Lewis JB, Li PKT, Maes BD, Neuen BL, Perrone RD, Remuzzi G, Schena FP, Wanner C, Wetzels JFM, Woodward M, Heerspink HJL; CKD-EPI Clinical Trials Consortium.

Nat Med. 2023 Jul;29(7):1867-1876. doi: 10.1038/s41591-023-02418-0. Epub 2023 Jun 17.

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IgA nephropathy: the lectin pathway and implications for targeted therapy.

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DNA binding protein YB-1 is a part of the neutrophil extracellular trap mediation of kidney damage and cross-organ effects - PubMed (nih.gov)

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J. Am. Soc. Nephrol., 2023 Jul; 34:241-257; https://doi.org/10.1681/ASN.2022040491

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NAR Genom Bioinform., 2023 Mar 3;5(1):lqad018.;  doi: 10.1093/nargab/lqad018. eCollection 2023 Mar.

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Prediction of heart transplant rejection from routine pathology slides with self-supervised deep learning - PubMed (nih.gov)

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Reduction of Endothelial Glycocalyx on Peritubular Capillaries in Chronic Kidney Disease - PubMed (nih.gov)

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Am J Pathol. 2023 Feb;193(2):138-147. doi: 10.1016/j.ajpath.2022.11.003. Epub 2022 Nov 19.

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Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner. 

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The Role of Platelet-Derived Growth Factor in Focal Segmental Glomerulosclerosis - PubMed (nih.gov)

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Nat. Commun., 2023 Jan 28;14(1):470.;  doi: 10.1038/s41467-023-36173-0.

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Stain-Independent Deep Learning-Based Analysis of Digital Kidney Histopathology - PubMed (nih.gov)

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scMEGA: single-cell multi-omic enhancer-based gene regulatory network inference. 

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Adult human kidney organoids originate from CD24+ cells and represent an advanced model for adult polycystic kidney disease - PubMed (nih.gov)

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Nat Genet. 2022 Nov;54(11):1690-1701. doi: 10.1038/s41588-022-01202-z. Epub 2022 Oct 27.

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Pro-oxidative priming but maintained cardiac function in a broad spectrum of murine models of chronic kidney disease - PubMed (nih.gov)

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TESTING the effects of corticosteroids in patients with IgA nephropathy

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Nephrol Dial Transplant. 2022 Jul 26;gfac221. doi: 10.1093/ndt/gfac221. Online ahead of print.

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Endogenous Modulation of Extracellular Matrix Collagen during Scar Formation after Myocardial Infarction - PubMed (nih.gov)

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Mapping the cardiac vascular niche in heart failure - PubMed (nih.gov)

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Using human iPSC-derived kidney organoids to decipher SARS-CoV-2 pathology on single cell level - PubMed (nih.gov)

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Predicting Future Outcomes from Kidney Biopsies with MCD/FSGS Lesions: Opportunities and Limitations - PubMed (nih.gov)

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Multiomic Spatial Mapping of Myocardial Infarction and Implications for Personalized Therapy - PubMed (nih.gov)

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Mapping the human kidney using single-cell genomics - PubMed (nih.gov)

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Corrigendum: The mast cell: A Janus in kidney transplants - PubMed (nih.gov)

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Front Immunol 2022, 14:1122409. doi: 10.3389/fimmu.2023.1183969.

 

Mapping Human Cardiac Sarcoidosis by Single Nuclear and Spatial Profiling - PubMed (nih.gov)

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Tackling stain variability using CycleGAN-based stain augmentation - PubMed (nih.gov)

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J Pathol Inform. 2022 Sep 13;13:100140. doi: 10.1016/j.jpi.2022.100140. eCollection 2022.

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Benchmarking weakly-supervised deep learning pipelines for whole slide classification in computational pathology - PubMed (nih.gov)

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Med Image Anal. 2022 Jul;79:102474. doi: 10.1016/j.media.2022.102474. Epub 2022 May 4.

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Current kidney function parameters overestimate kidney tissue repair in reversible experimental kidney disease - PubMed (nih.gov)

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Kidney Int. 2022 Aug;102(2):307-320. doi: 10.1016/j.kint.2022.02.039. Epub 2022 Apr 26.

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Spatial multi-omic map of human myocardial infarction. 

Kuppe C, Ramirez Flores RO, Li Z, Hayat S, Levinson RT, Liao X, Hannani MT, Tanevski J, Wünnemann F, Nagai JS, Halder M, Schumacher D, Menzel S, Schäfer G, Hoeft K, Cheng M, Ziegler S, Zhang X, Peisker F, Kaesler N, Saritas T, Xu Y, Kassner A, Gummert J, Morshuis M, Amrute J, Veltrop RJA, Boor P, Klingel K, Van Laake LW, Vink A, Hoogenboezem RM, Bindels EMJ, Schurgers L, Sattler S, Schapiro D, Schneider RK, Lavine K, Milting H, Costa IG, Saez-Rodriguez J, Kramann R.

Nature. 2022 Aug;608(7924):766-777. doi: 10.1038/s41586-022-05060-x. Epub 2022 Aug 10.

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How I Treat IgA Nephropathy

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CJASN August 2022, 17 (8) 1243-1246. Doi.org/10.2215/CJN.02710322

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Assessing prognosis in IgA nephropathy - PubMed (nih.gov)

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MOJITOO: a fast and universal method for integration of multimodal single-cell data - PubMed (nih.gov)

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Improving unsupervised stain-to-stain translation using self-supervision and meta-learning - PubMed (nih.gov)

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What We Have Learned so far From Single Cell Sequencing in Acute Kidney Injury - PubMed (nih.gov)

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Dis. Model Mech.; 2022 Jun 8; 15:dmm046342; https://doi.org/10.1242/dmm.046342

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Large-scale extraction of interpretable features provides new insights into kidney histopathology - A proof-of-concept study - PubMed (nih.gov)

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J Pathol Inform. 2022 May 25;13:100097. doi: 10.1016/j.jpi.2022.100097. eCollection 2022.

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Current kidney function parameters overestimate kidney tissue repair in reversible experimental kidney disease

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Kidney Int April 2022 doi: 10.1016/j.kint.2022.02.039

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Parietal epithelial cells maintain the epithelial cell continuum forming Bowman's space in focal segmental glomerulosclerosis - PubMed (nih.gov)

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Chemokine CCL9 Is Upregulated Early in Chronic Kidney Disease and Counteracts Kidney Inflammation and Fibrosis - PubMed (nih.gov)

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Renal Denervation Prevents Atrial Arrhythmogenic Substrate Development in CKD - PubMed (nih.gov)

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Coagulation-independent effects of thrombin and factor Xa: role of protease-activated receptors in pulmonary hypertension

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Carbamylated sortilin associates with cardiovascular calcification in patients with chronic kidney disease

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Activation of Notch3 in Renal Tubular Cells Leads to Progressive Cystic Kidney Disease - PubMed (nih.gov)

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Reproducibility Evaluation of Urinary Peptide Detection Using CE-MS - PubMed (nih.gov)

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A Hypercaloric Diet Induces Early Podocyte Damage in Aged, Non-Diabetic Rats - PubMed (nih.gov)

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Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen - PubMed (nih.gov)

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Effects of Perfusion Pressures on Podocyte Loss in the Isolated Perfused Mouse Kidney

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